Normalizing Sample Concentrations

One of the most tedious tasks in the molecular laboratory is normalizing raw DNA or RNA samples to a specified concentration. Done manually, this process is especially demanding as the amount of sample and diluent required for each normalization must first be calculated, followed by careful re-adjustment of hand pipettor settings for each and every pipetting event in the process.

The CAS-1200 calculates all required sample and diluent volumes then pipettes them accordingly, making normalization extremely simple as shown in the example (opposite).

Normalization of DNA concentration
When setting up a run, simply indicate (A) the starting concentration of each sample and (B) the final concentration and volume required for normalized samples. The software then calculates and displays the amount of sample and diluent it will use to normalize each sample (C).