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HRM Publications
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Click here to view publications list in PDF format, grouped by area of specialisation |
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High-resolution melt analysis to identify and map sequence-tagged site anchor points onto linkage maps: a white lupin (Lupinus albus) map as an exemplar
Croxford AE, Rogers T, Caligari PDS, Wilkinson MJ
New Phytologist, Published Online: 5 August 2008
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Molecular analysis of the parkin gene in South African patients diagnosed with Parkinson's disease
Bardien S, Keyser R, Yako Y, Lombard D, Carr J
Parkinsonism Related Disorders. May 29 2008 (Epub ahead of print)
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Interleukin-10 promoter polymorphisms influence susceptibility to ulcerative colitis in a gender-specific manner
Andrea Tedde, Anna Laura Putignano, Siro Bagnoli, Caterina Congregati, Monica Milla, Sandro Sorbi, Maurizio Genuardi, Laura Papi
Scandanavian Journal of Gastroenterology: 06 February 2008 |
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No Association Between the LRRK2 G2019S Mutation and Alzheimer’s disease in Italy
Andrea Tedde, Silvia Bagnoli, Elena Cellini, Benedetta Nacmias, Silvia Piacentini, Sandro Sorbi
Cell Mol Neurobiol (2007) 27:877–881
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Direct Genotyping of Single Nucleotide Polymorphisms in Methyl Metabolism Genes Using Probe-Free High-Resolution Melting Analysis
Lasse S. Kristensen and Alexander Dobrovic
Cancer Epidemiology Biomarkers & Prevention 17, 1240-1247, May 1, 2008
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Detection of knockdown resistance (kdr) mutations in Anopheles gambiae: a comparison of two new high-throughput assays with existing methods
Chris Bass, Dimitra Nikou, Martin J Donnelly, Martin S Williamson, Hilary Ranson, Amanda Ball, John Vontas and Linda M Field
Malaria Journal 2007, 6:111
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Differentiation between vaccine and wild-type varicella-zoster virus genotypes by high-resolution melt analysis of single nucleotide polymorphisms
Cheryl Toi, Dominic Dwyer
J Clin Virol. 2008 May 12. [Epub ahead of print]
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Rapid detection of methylation change at H19 in human imprinting disorders using methylation-sensitive high-resolution melting
Tomasz K. Wojdacz, Alexander Dobrovic, and Elizabeth M. Algar
HUMAN MUTATION 0,1-6, 2008
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De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy
Hirotomo Saitsu, Mitsuhiro Kato, Takeshi Mizuguchi, Keisuke Hamada, Hitoshi Osaka, Jun Tohyama, Katsuhisa Uruno, Satoko Kumada, Kiyomi Nishiyama, Akira Nishimura, Ippei Okada, Yukiko Yoshimura, Syu-ichi Hirai, Tatsuro Kumada, Kiyoshi Hayasaka, Atsuo Fukuda, Kazuhiro Ogata & Naomichi Matsumoto
Nature Genetics advance online publication, published online: 11 May 2008
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High-Resolution Melt Analysis for the Detection of a Mutation Associated with Permethrin Resistance in a Population of Scabies Mites
C Pasay, L Arlian, M Morgan, D Vyszenski-Moher, A Rose, D Holt, S Walton, J McCarthy
Medical and Veterinary Entomology (2008) 22, 82-88
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High-Resolution Melting Analysis of the spa Repeat Region of Staphylococcus aureus
Alex J. Stephens, John Inman-Bamber, Philip M. Giffard and Flavia Huygens
Clinical Chemistry 54: 432-436, 2008; 10.1373/clinchem.2007.093658
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Sensitive Melting Analysis after Real-Time Methylation Specific PCR (SMART-MSP): high-throughput and probe-free quantitative DNA methylation detection
Lasse S. Kristensen1,2, Thomas Mikeska1, Michael Krypuy1, Alexander Dobrovic1,3*
Nucleic Acids Research 2008, doi: 10.1093/nar/gkn113
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Detection of alpha-thalassemia-1 Southeast Asian type using real-time gap-PCR with SYBR Green1 and High Resolution Melting analysis
Sakorn Pornprasert1, Arunee Phusua2, Sudjai Suanta2, Rattika Saetung2, Torpong Sanguansermsri2
European Journal of Haematology 2008
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BRCA1 promoter methylation in peripheral blood DNA of mutation negative familial breast cancer patients with a BRCA1 tumour phenotype
Cameron Snell, Michael Krypuy, Ee Ming Wong, Maurice B Loughrey and Alexander Dobrovic
Breast Cancer Research 2008, 10:R12doi:10.1186/bcr1858
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Development of an affordable, sensitive and rapid screening method for mutation detection in UK FH subjects
Christina Hubbart, Ros Whittall, Marileia Scartezini, Steve E. Humphries
Centre for Cardiovascular Genetics, British Heart Foundation Laboratories, The Rayne Building, Royal Free and UCL Medical School, London WC1E 6JF, UK
j.atherosclerosis.2007.04.032
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High-Resolution Melting for Accurate Assessment of DNA Methylation
Christina Dahl and Per Guldberg
Clinical Chemistry 53: 1877-78, 2007
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High resolution melting for mutation scanning of TP53 exons 5-8
Michael Krypuy, Ahmed Ashour Ahmed, Dariush Etemadmoghadam, Sarah J Hyland, Australian Ovarian Cancer Study Group, Anna deFazio, Stephen B Fox, James D Brenton, David D Bowtell and Alexander Dobrovic
BMC Camcer 2007, 7:168
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Methylation-Sensitive High-Resolution Melting-Curve Analysis of the SNRPN Gene as a Diagnostic Screen for Prader-Willi and Angelman Syndromes
Helen E White, Victoria J Hall and Nicholas C.P. Cross
Clinical Chemistry 52, No. 11, 2007
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Classification of Mycoplasma Synoviae Strains Using Single-Stranded Conformation Polymorphism and High-Resolution Melting-Curve Analysis of the vlhA Gene Single-Copy Region
Nathan N Jeffrey, Robin B Gasser, Penelope A Steer and Amir H Noormohammadi
Microbiology (2007), 153, 2679-2688
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Factor V Leiden (G1691A) and Prothrombin (G20210A) Genotyping by High Resolution Melt Analysis (HRM) and Syto9 Flourescent Dye on the Rotor-Gene 6000 HRM device
Ameziane N, Bogard M, Lamoril J, Bouizegareene P, Gourlin N, Kaiser T, Erba G, Tchernitchkou D, Trichet C, Guiet P and Herve C
View Poster presented at XXIst Congress of the International Society on Thrombosis and Haemostasis. Geneva 2007, July 6-12 (140kb PDF) |
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Methylation-Sensitive High Resolution Melting (MS-HRM): A New Approach for Sensitive and High-Throughput Assessment of Methylation
Tomasz K Wojdacz and Alexander Dobrovic
Nucleic Acids Research, 2007, doi:10.1093/nar/gkm013
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High-Resolution DNA Melt Curve Analysis of the Clustered Regularly Interspaced Short-Palindromic-Repeat Locus of Campylobacter jejuni
Erin P. Price, Helen Smith, Flavia Huygens, and Philip M. Giffard
Applied and Environmental Microbiology, 2007, p.1-2 Vol. 73 (10)
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High Resolution Melt Analysis to Identify Non-Compatible Sibling Donors for HSCT Patients
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Peter Duignan, Kim Jennings, Andrea Tesoriero, Heather Hondow, Michael Varney, Rhonda Holdsworth, and Brian Tait
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Use of DNA Melting Simulation Software for In-Silico Diagnostic Assay Design: Targeting Regions with Complex Melting Curves and Confirmation by Real-Time PCR Using Intercalating Dyes
John P Rasmussen, Christopher P Saint and Paul T Monis
BMC Bioinformatics, 2007, 8:107 doi:10.1186/1471-2105-8-107
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Expanded Instrument Comparison of Amplicon DNA Melting Analysis for Mutation Scanning and Genotyping
Mark G Herrmann, Jacob D Durtschi, Carl T Wittwer, Karl V Voelkerding
Clinical Chemistry 53, No. 8, 2007(b)
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Instrument Comparison for Heterozygote Scanning of Single and Double Heterozygotes: A Correction and Extension of Herrmann et al., Clin Chem 2006; 52:494-503
Mark G Herrmann, Jacob D Durtschi, L. Kathryn Bromley, Carl T Wittwer and Karl V Voelkerding
Clinical Chemistry 53:150-152, 2007(a)
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Amplicon DNA Melting Analysis for Mutation Scanning and Genotyping: Cross-Platform Comparison of Instruments and Dyes
Mark G Herrmann, Jacob D Durtschi, L. Kathryn Bromley, Carl T Wittwer and Karl V. Voelkerding
Clinical Chemistry 52:3 494-503 (2006)
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High Resolution Melting Analysis for the Rapid and Sensitive Detection of Mutations in Clinical Samples: KRAS Codon 12 and 13 Mutations in Non-Small Cell Lung Cancer
Michael Krypuy, Genni M Newnham, David M Thomas, Matthew Conron and Alexander Dobrovic
BMC Cancer 2006, 6:295 doi: 10.1186/1471-2407-6-295
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Mutation Scanning by High Resolution Melt Analysis. Evaluation of Rotor-Gene 6000 (Corbett Life Science), HR-1 and 384-well LightScanner (Idaho Technology)
White H and Potts G.
National Genetics Reference Laboratory (Wessex, 2006)
NHS Technology Assessment Report
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Genotyping of Single-Nucleotide Polymorphisms by High Resolution Melting of Small Amplicons
Michael Liew, Robert Pryor, Robert Palais, Cindy Meadows, Maria Erali, Elaine Lyon and Carl Wittwer
Clinical Chemistry 50: 1156-1164, 2004; 10.1373/clinchem.2004.032136
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